Side Effects of Dental Acne MedicationsOral acne medicines deal with the problem from within your body by subduing hormones that stimulate oil production. These include anti-biotics such as tetracycline (Tetracin, Tetracap) and minocycline (Solodyn, Minocin) and the pill called spironolactone (Aldactone).Some oral drugs are offered over-the-counter